Backside-up pattern preparation for the LC-MS/MS quantification of anti-cancer monoclonal antibodies in bio matrices Therapeutic monoclonal antibodies (mAbs) are quickly taking up the therapy of many malignancies, and an astonishing variety of mAbs is in improvement. This causes a excessive demand for quantification of mAbs in biomatrices each for measuring therapeutic mAb concentrations and to assist pharmacokinetics […]
Tuning Monoclonal Antibody Galactosylation using Raman Spectroscopy
Tuning Monoclonal Antibody Galactosylation using Raman Spectroscopy-Controlled Lactic Acid Feeding A key aspect of large-scale production of biotherapeutics is a well-designed and consistently-executed upstream cell culture process. Process Analytical Technology (PAT) tools provide enhanced monitoring and control capabilities to support consistent process execution, and also have potential to aid in maintenance of product quality at desired levels. […]
Receptor-binding domain-specific human neutralizing monoclonal antibodies
Receptor-binding domain-specific human neutralizing monoclonal antibodies in opposition to SARS-CoV and SARS-CoV-2 The outbreaks of extreme acute respiratory syndrome (SARS) and Coronavirus Illness 2019 (COVID-19) attributable to SARS-CoV and SARS-CoV-2, respectively, have posed extreme threats to international public well being and the economic system. Remedy and prevention of those viral illnesses name for the analysis and improvement […]
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